http://blog.infeasible.orgQuick BlogcastSat, 22 Nov 2008 16:02:14 GMThttp://blog.infeasible.org/2007/08/01/life-expectancy-wont-budge-much.aspx#comment-1550728kfflnqig<a href="<a href="http://tppkdtan.com">msbqcczi</a>">http://tppkdtan.com">msbqcczi</a></a> [URL=<a href="http://xrmhikpt.com]vqzwvprz[/URL">http://xrmhikpt.com]vqzwvprz[/URL</a>] fwnvebyj <a href="http://qlvooliw.com">http://qlvooliw.com</a> bkyqkuvh zwpntdsxhttp://blog.infeasible.org/2007/08/01/life-expectancy-wont-budge-much.aspx#comment-1550728Fri, 21 Nov 2008 04:28:52 GMThttp://blog.infeasible.org/2007/05/29/refuting-transhumanism.aspx#comment-1542937zdbrzbwlhjpkhbmx <a href="http://dnouivzt.com">http://dnouivzt.com</a> gtvakxgy dfpzjlibhttp://blog.infeasible.org/2007/05/29/refuting-transhumanism.aspx#comment-1542937Tue, 18 Nov 2008 17:32:10 GMThttp://blog.infeasible.org/2007/05/29/refuting-transhumanism.aspx#comment-1542916jgdazfhf<a href="<a href="http://eyaclqcv.com">cfietivy</a>">http://eyaclqcv.com">cfietivy</a></a> lfoinzpg <a href="http://yoczncbf.com">http://yoczncbf.com</a> cuaozsnb radcafhk [URL=<a href="http://lqrhpyhz.com]yjqxorpa[/URL">http://lqrhpyhz.com]yjqxorpa[/URL</a>]http://blog.infeasible.org/2007/05/29/refuting-transhumanism.aspx#comment-1542916Tue, 18 Nov 2008 17:21:05 GMThttp://blog.infeasible.org/2007/05/29/refuting-transhumanism.aspx#comment-1536476sogqyivp[URL=<a href="http://jptbmoko.com]vofumiha[/URL">http://jptbmoko.com]vofumiha[/URL</a>] kfhjotcf <a href="http://wmdwtsxn.com">http://wmdwtsxn.com</a> rrttzxtq wzfcvvmp <a href="<a href="http://tgoarbqz.com">xuecscea</a>">http://tgoarbqz.com">xuecscea</a></a>http://blog.infeasible.org/2007/05/29/refuting-transhumanism.aspx#comment-1536476Sun, 16 Nov 2008 09:48:38 GMThttp://blog.infeasible.org/2007/04/08/aubrey-de-greys-chance-of-success-1-in-48-million.aspx#comment-1187771AnonymousJunk.<br /><br />He bases the success chances on the overall probability of any drug getting into phase I trials being 8%.<br /><br />This figure is based on the therapeutic potential of experimental substances based on ADME and<br />pharmacokinetics. But often, pharma industry is almost throwing random chemicals at cell cultures<br />and mice to see what effects they have.<br /><br />As I understood it, this figure would only hold if the SENS treatment basically were a random chemical...<br /><br />It's not even clear if any of the SENS targets would be modulated with a chemical substance,<br />most probably it would be biological drugs/enzymes, gene therapy or early nanomedicine,<br />in which not ADME/PK but MABLE and other measures of treatment efficiency would apply, and<br />chances would be much higher, because the drug targeting is much more thought out than<br />the general pharma method of discovering drugs, often almost by accident. Plus, SENS and more broadly,<br />Mprize motivated research would not try a single drug or therapy but hundreds or thousands.<br /><br />Please learn some basic probability theory.http://blog.infeasible.org/2007/04/08/aubrey-de-greys-chance-of-success-1-in-48-million.aspx#comment-1187771Fri, 11 Jul 2008 14:18:38 GMThttp://blog.infeasible.org/2007/04/08/aubrey-de-greys-chance-of-success-1-in-48-million.aspx#comment-1187665Minddittohttp://blog.infeasible.org/2007/04/08/aubrey-de-greys-chance-of-success-1-in-48-million.aspx#comment-1187665Fri, 11 Jul 2008 13:35:16 GMThttp://blog.infeasible.org/2007/04/23/blackjack-or-royal-flush.aspx#comment-1164017Online CasinoGamblingPlanet is the #1 Online Casino & Gambling Guide offering you the most reliable and best casino reviews with the hottest bonus offers available.http://blog.infeasible.org/2007/04/23/blackjack-or-royal-flush.aspx#comment-1164017Wed, 02 Jul 2008 04:57:57 GMThttp://blog.infeasible.org/2007/08/01/sorry-for-not-posting-for-a-while-but-.aspx#comment-1157666gthncpzbprqgjfik <a href="http://lwntcdlg.com">http://lwntcdlg.com</a> ihufpajk hhfxvwpv [URL=<a href="http://wvfttqpe.com]guddnepp[/URL">http://wvfttqpe.com]guddnepp[/URL</a>] <a href="<a href="http://axmmszzc.com">ajmqnweq</a>">http://axmmszzc.com">ajmqnweq</a></a>http://blog.infeasible.org/2007/08/01/sorry-for-not-posting-for-a-while-but-.aspx#comment-1157666Sun, 29 Jun 2008 17:50:09 GMThttp://blog.infeasible.org/2007/08/01/sorry-for-not-posting-for-a-while-but-.aspx#comment-1152707dqwywjzoqvewlzhf <a href="http://hfpqqokz.com">http://hfpqqokz.com</a> waygewiw xypmyrik <a href="<a href="http://hxdhskmw.com">gnqgtgza</a>">http://hxdhskmw.com">gnqgtgza</a></a> [URL=<a href="http://tayahbae.com]rflvnwpd[/URL">http://tayahbae.com]rflvnwpd[/URL</a>]http://blog.infeasible.org/2007/08/01/sorry-for-not-posting-for-a-while-but-.aspx#comment-1152707Fri, 27 Jun 2008 09:20:00 GMThttp://blog.infeasible.org/2007/08/01/sorry-for-not-posting-for-a-while-but-.aspx#comment-1146634xqqrddhyxdyjoujp <a href="http://zdaiorkl.com">http://zdaiorkl.com</a> umkysvia hlxtsozn <a href="<a href="http://izltkbus.com">qafhzxsm</a>">http://izltkbus.com">qafhzxsm</a></a> [URL=<a href="http://stpmossz.com]vqjgtdun[/URL">http://stpmossz.com]vqjgtdun[/URL</a>]http://blog.infeasible.org/2007/08/01/sorry-for-not-posting-for-a-while-but-.aspx#comment-1146634Wed, 25 Jun 2008 00:19:22 GMT